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Cambiarenes: Single-Step Synthesis and Anion Binding of a Clip- Shaped Macrocycle with a Redox-Active Core

preprint
submitted on 10.09.2019 and posted on 12.09.2019 by Riley J. Petersen, Brett J. Rozeboom, Shalisa Oburn, Nolan Blythe, Tanner Rathje, Javier Luna, Steven Kibby, Emily O'Brien, Kayleigh Rohr, Joshua Carpenter, Taylor Sanders, Andrew Johnson, Kristin Hutchins, Scott Shaw, Leonard MacGillivray, Jay Wackerly
We report the synthesis of a novel macrocyclic host molecule that forms in a single step from commercially available starting materials. The core of the macrocycle backbone possesses two quinone rings and, thus, is redox-active. Host-guest binding involving the clip-shaped cavity indicates selective binding of pyridine N-oxides based of the electron density of and steric bulk of the anionic oxygen.

Funding

#52318-UNI

DMR-1708673

History

Email Address of Submitting Author

wackerlyj@central.edu

Institution

Central College

Country

United States

ORCID For Submitting Author

0000-0001-6975-4431

Declaration of Conflict of Interest

The authors declare no conflict of interest.

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