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A_fluorescent_ceriumbased_biosensor_for_the_direct_visual_detection_of_phosphate_under_physiological_conditions-2020-12-23-08-14.pdf (1.03 MB)

An astonishing simple cerium-based chemosensor for fluorescent selective phosphate detection in aquaeous medium

preprint
revised on 23.12.2020, 08:17 and posted on 24.12.2020, 05:44 by Thibaud Rossel

Phosphate ions are socially important chemicals. They are involved in crucial processes such as for example in medicine or agriculture. However, their sensing with a chemosensor is ardous due to their chemical properties. In this context, a remarkable chemosensor would reveal an outstanding affinity, a high selectivity and a low detection limit in favor of an analyte. This has long been addressed in the past by chemists in synthesizing com- plex chemical architectures as receptors but with questionable successes. Astonishingly, here, for phosphate detection, we address this problem profiting by a simple fluorescent indicator displacement assay (FID) with only commercially available chemicals. We used cerium ammonium nitrate (CAN) combined with a fluorophore to probe phosphate ions in aqueous mediums. The inorganic complex detects phosphate ions in low millimolar concentrations either spectrophotometrically or with the naked-eye with high selectivity and affinity over other anions. To our knowledge, this is the first description of a simple sensitive, selective and high affinity cerium-based chemosensor for the fluorescent selective naked-eye detection of phosphate in aqueous medium. It proved useful for the detection of phosphate in Coca-Cola©.

Funding

No fundings

History

Email Address of Submitting Author

thibaud.rossel@emsp.gfbienne.ch

Institution

Gymnase français de Bienne

Country

Switzerland

ORCID For Submitting Author

0000-0003-0254-5445

Declaration of Conflict of Interest

No conflict of interest

Version Notes

Paper version 2

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