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A Single-Step Synthesis of 1,3,4,6-Tetraaryl-5-Aryliminopiperazin-2-One

submitted on 26.05.2020, 11:52 and posted on 27.05.2020, 11:56 by Moustafa El-Araby, Abdelsattar Omar
We report here novel reaction that we found unprecedented, up to our knowledge. In a single step, we obtained unusual result. After magnificent efforts we could deduce the structure. We confirmed the structure of this product by reproducing the reaction using other substrates. The reaction therefore resulted in a piperazine ring that is functionalized on every atom in the ring. This was stage 1. We almost finished making this reaction more utilizable (stage 2) in a future paper. Enjoy it because you won't see a new chemistry everyday.


This project was funded by the Deanship of Scientific Research (DSR), King Abdulaziz University, Jeddah, the Kingdom of Saudi Arabia, under grant number RG-3-166-38.


Email Address of Submitting Author


King Abdulaziz University


Saudi Arabia

ORCID For Submitting Author


Declaration of Conflict of Interest

Authors declare no conflict of interest

Version Notes

First Version, pending revise after peer reviewing