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A_molecular_logic_gate_for_the_nakedeye_detection_of_gluthatione_or_pyrophosphate_with_a_nickel_based_biosensor-2020-04-17-07-38.pdf (783.79 kB)
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A Molecular Logic Gate for the Naked-Eye Detection of Gluthatione or Pyrophosphate with a Nickel Based Bio-Sensor

preprint
submitted on 08.04.2020 and posted on 21.04.2020 by Thibaud Rossel

An inorganic water soluble Ni(II) complex offers a molecular logic gate for the naked-eye detection of pyrophosphate versus thiol derivatives. Pyrocathecol coordinated to nickel performs a thiol-michael addition click reaction in the presence of thiol derivativs whereas pyrophosphate allows a displacement of the indicator PCV leading to an indicator displacement assay.

Funding

No fundings

History

Email Address of Submitting Author

thibaud.rossel@emsp.gfbienne.ch

Institution

Gymnase français de Bienne

Country

Switzerland

ORCID For Submitting Author

0000-0003-0254-5445

Declaration of Conflict of Interest

no conflict of interest

Version Notes

version 1 (early working paper)

Exports