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A Minimalistic Hydrolase Based on Co-Assembled Cyclic Dipeptides

01 October 2019, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

This paper describes minimalistic cyclic dipeptides acting as esterase-mimicks in a self-assembled hydrogel state. It demonstrates that cyclic dipeptides could have acted as enzyme-precursors on a primordial earth and hence be important for abiogenesis.

Keywords

chemical evolution
Organocatalyst
esterase-like activities
Enzyme Mimics
hydrogels

Supplementary materials

Title
Description
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Title
manuscript DKPs ChemRxiv
Description
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SI DKP ChemRxiv
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Now Published

A minimalistic hydrolase based on co-assembled cyclic dipeptides [opens in a new tab]
Alexander J. Kleinsmann, Boris J. Nachtsheim journal article
Organic & Biomolecular Chemistry , Volume 18, Issue 1
Online publication date: 2020

Version History

Oct 01, 2019 Version 1

Version Notes

initial version

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The content is available under CC BY NC ND 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv.9919325.v1
D O I: 10.26434/chemrxiv.9919325.v1 [opens in a new tab]

Author’s competing interest statement

no conflict of interest

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