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A General Approach for Encapsulation of Biomolecules Using MOF Particles
preprintsubmitted on 12.03.2020, 01:18 and posted on 12.03.2020, 11:06 by Da Zou, Lei Yu, Qi Sun, Yue Hui, Teng Jisi, Yun Liu, Guangze Yang, David Wibowo, Chun-Xia Zhao
Encapsulation of biomoleucles in metal organic frameworks (MOFs) has recently attracted significant interest because of the benign process including room temperature, neutral pH and without the requirement of any other chemical reagents. Also, these biomolecule incorporated MOFs (biomolecules@MOFs) have demonstrated their potential in biomolecule protection and controlled release for various applications such as drug delivery, vaccines, etc. This work aims to develop a general strategy to make biomolecules@MOFs via a biomimetic mineralization process.