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A General Approach for Encapsulation of Biomolecules Using MOF Particles

preprint
submitted on 12.03.2020 and posted on 12.03.2020 by Da Zou, Lei Yu, Qi Sun, Yue Hui, Teng Jisi, Yun Liu, Guangze Yang, David Wibowo, Chun-Xia Zhao
Encapsulation of biomoleucles in metal organic frameworks (MOFs) has recently attracted significant interest because of the benign process including room temperature, neutral pH and without the requirement of any other chemical reagents. Also, these biomolecule incorporated MOFs (biomolecules@MOFs) have demonstrated their potential in biomolecule protection and controlled release for various applications such as drug delivery, vaccines, etc. This work aims to develop a general strategy to make biomolecules@MOFs via a biomimetic mineralization process.

Funding

Australian Research Council Discovery Project DP150100798

Australian Research Council Linkage project LP140100424

Australian Research Council Future Fellowship FT140100726

History

Email Address of Submitting Author

z.chunxia@uq.edu.au

Institution

The University of Queensland

Country

Australia

ORCID For Submitting Author

0000-0002-3365-3759

Declaration of Conflict of Interest

No conflict of interest

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