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A_dinuclear_copper_based_artificial_metalloenzyme_for_the_kinetic_resolution_of_adrenalin-2020-04-17-10-06.pdf (1.02 MB)
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A Dinuclear Copper Based Artificial Metalloenzyme for the Kinetic Resolution of Adrenalin

preprint
submitted on 17.04.2020 and posted on 20.04.2020 by Thibaud Rossel
Incorporation of a copper catalyst within carbonic anhydrase affords artificial metalloenzyme for the oxidation of catechols in aqueous solution at physiological pH. Optimization of the performance can be achieved either by chemical or genetic means. In addition, a model of enzyme/inhibitor is proposed and discussed.

Funding

no fundings

History

Email Address of Submitting Author

thibaud.rossel@emps.gfbienne.ch

Institution

Gymnase français de Bienne

Country

Switzerland

ORCID For Submitting Author

0000-0003-0254-5445

Declaration of Conflict of Interest

No conflict of interest

Version Notes

Paper version 1

Exports