ChemRxiv
These are preliminary reports that have not been peer-reviewed. They should not be regarded as conclusive, guide clinical practice/health-related behavior, or be reported in news media as established information. For more information, please see our FAQs.
1/1
2 files

A Cost-Effective and Eco-Friendly Way to Dihydroxylate Terminal and Internal Alkenes Using Hydrogen Peroxide/formic Acid

preprint
revised on 04.12.2020, 17:14 and posted on 07.12.2020, 07:23 by Chia-Wei Hsu, Trevor Dzwiniel, Krzysztof Pupek

Abstract In this report, we present a modified dihydroxylation procedure for terminal and internal alkenes under neat conditions using formic acid and hydrogen peroxide. Upon the in situ formation of performic acid, followed by the hydrolysis of hydroxy-formoxy compounds with excess water, we can obtain a series of diols without catalysts and bases.

Funding

Argonne National Laboratory is a U. S. Department of Energy Office of Science laboratory operated by UChicago Argonne, LLC, under contract DE-AC02-06CH11357. The work published is sponsored by DOE EERE Vehicle Technology Office

History

Email Address of Submitting Author

tdzwiniel@anl.gov

Institution

Argonne National Laboratory

Country

United States

ORCID For Submitting Author

0000-0002-7653-3554

Declaration of Conflict of Interest

The authors declare no conflict of interest.

Version Notes

first version

Exports

ChemRxiv

Exports