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比赛用-JCR-201905-synthesis of CoQ1.doc (574.5 kB)
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A Convenient Two-Step Synthesis of Coenzyme Q1

preprint
submitted on 12.05.2019 and posted on 15.05.2019 by Yi-Yu Yan, Wan-Yue Luo, Yan Zhao, Jian-Hua Tian, Jin Wang

A convenient method for the preparation of Coenzyme Q1 from the cheap and readily available 3,4,5-Trimethoxytoluene was developed. CoQ1 was synthesized in moderate yield by a two-step procedure involving the key reaction of allyl bromide with CoQ0 through a redox chain reaction. The reaction is efficient and could be used for the synthesis of other CoQ compounds.

History

Email Address of Submitting Author

wangj01@yctu.edu.cn

Institution

Yancheng Teachers University

Country

China

ORCID For Submitting Author

0000-0002-2929-6381

Declaration of Conflict of Interest

no conflict of interest

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