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we discuss the potential of targeting Dihydroorotate dehydrogenase enzyme to
help treat Covid 19. Next, we present a very large scale of docking analysis using
7900 drug candidates and 20 Dihydroorotate dehydrogenase structures. Our
findings not only identify 28-FDA approved candidate molecules, but also show common
characteristics among the candidates, especially their association with serotonin-dopamine
receptors. In continuation, we discuss the existing clinical trials for Covid
19 treatment of some of the drug candidates we have identified, supporting that
the rest are good candidates.