AT-CuAAC Synthesis of Mechanically Interlocked Oligonucleotides

07 February 2020, Version 1
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

We present a simple strategy for the synthesis of main chain oligonucleotide rotaxanes with precise control over the position of the macrocycle. The novel DNA-based rotaxanes were analyzed to assess the effect of the mechanical bond on their properties.

Keywords

rotaxanes
oligonucleotides
supramolecular
Mechanically Interlocked Architectures

Supplementary materials

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2020 02 04 ESI Acevedo Rot DNA
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