1,2-Dicarbonyl Radicals with Exceptional Physiological and Chemical Stability

The present manuscript describes the design, synthesis, and characterization of the most stable organic radical reported up to date.

Here we report:
▪ Synthesis and full characterization including X-ray structure of stable 1,2-dicarbonyl radicals
▪ Proposed mechanism for the formation of the presented radicals
▪ Redox reactivity of the radicals
▪ Stability of the radicals under various organic and inorganic conditions
▪ Demonstration of the radicals as potential organic radical contrast agent candidate