Virtual Screening of an FDA Approved Drugs Database on Two COVID-19 Coronavirus Proteins
2020-02-13T13:29:45Z (GMT) by
The infection by the 2019-nCoV coronavirus (COVID-19) is a world-wide emergency.
The crystal structure of a protein essential for virus replication has been filed in the Protein Data
Bank recently. Additionally, homology models of 24 COVID-19 proteins were made available by
the Zhang group. In this paper, we present results deriving from the virtual screening of a database
of more than 3000 FDA approved drugs on two distinct targets. Results showed that some of the
known protease inhibitors currently used in HIV infections might be helpful for the therapy of