Unrestrictive protein modification localization and quality control for open search of mass spectra

2018-01-18T15:33:50Z (GMT) by Zhiwu An Fuzhou Gong Yan Fu
We have developed PTMiner, a first software tool for automated, confident filtering, localization and annotation of protein post-translational modifications identified by open (mass-tolerant) search of large tandem mass spectrometry datasets. The performance of the software was validated on carefully designed simulation data. <br>