Small-Molecule (Micro)arrays for Sensitive Multiplex Metabolites Detection by Surface Plasmon Resonance Imaging

2018-03-01T15:13:52Z (GMT) by Yong Cao Mark T. McDermott
<div> <div> <div> <p>Small-molecule (micro)arrays were developed to measure three metabolites simultaneously by surface plasmon resonance imaging for the first time. To tackle the low sensitivity challenge associated with small molecule detection, antibodies were employed as the signal amplifiers. This work demonstrates both inhibition and displacement formats are applicable for sensitive multiplex metabolites detection. </p> </div> </div> </div>