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Sankaran_Optoregulated Protein Release_ChemRXiv.pdf (694.35 kB)

Optoregulated Protein Release from an Engineered Living Material

preprint
submitted on 23.07.2018, 20:13 and posted on 24.07.2018, 13:58 by Shrikrishnan Sankaran, Aránzazu del Campo
An engineered living material for light-regulated protein release is realized by combining optogenetics, bacterial protein secretion and hydrogels. Hydrogel-immobilized bacteria are optogenetically programmed to express and secrete a fluorescent protein in response to light irradiation. Using light, tunability and localized confinement of protein expression along with dosing of protein release are demonstrated.

History

Email Address of Submitting Author

shrikrishnan.sankaran@leibniz-inm.de

Email Address(es) for Other Author(s)

aranzazu.delcampo@leibniz-inm.de

Institution

INM – Leibniz-Institut für Neue Materialien gGmbH

Country

Germany

ORCID For Submitting Author

0000-0001-6251-585X

Declaration of Conflict of Interest

No conflict of interest

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