Mild Temperature Copper-Catalyzed Amination of Aryl Halides with Aqueous Ammonia in the Presence of Pyridyldiketone Ligands

25 February 2019, Version 2
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

Ambidentate ligand pyridyldiketones were used in combination with copper to catalyze amination of aryl halides under very mild temperatures with aqueous ammonia. This novel catalytic system allow efficient coupling in one of the smoothest conditions ever reported in literature.

Keywords

Homogeneous catalysis
cross coupling reactions
copper catalyst
diketone ligands
ammonia aqueous

Supplementary materials

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