Highly Enantioselective Hiyama Cross-Coupling via Rh-Catalyzed Allylic Arylation of Racemic Allyl Chlorides

13 August 2018, Version 1
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

Highly enantioselective Hiyama cross-coupling reactions have been achieved through rhodium(I)-catalyzed dynamic kinetic asymmetric transformations between aryl siloxanes and racemic allyl halides. This process affords valuable enantiomerically enriched allyl arenes and is compatible with heterocyclic allyl chloride electrophiles.

Keywords

Hiyama Coupling
DYKAT
Allylation

Supplementary materials

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Supporting Information - Rh Hiyama Allyl
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