Genetically Tunable Enzymatic C‒H Amidation for Lactam Synthesis

2019-02-13T17:02:35Z (GMT) by Inha Cho Zhijun Jia Frances H. Arnold
<p>Directed evolution of cytochrome P450 enzymes fine-tunes site selectivity of new-to-nature C‒H amidation for modular, sustainable and scalable preparation of enantio-enriched β-, γ- and δ-lactams.<br></p><p></p>