Exploring the Active Compounds of Traditional Mongolian Medicine in Intervention of Novel Coronavirus (2019-nCoV) Based on Molecular Docking Method

2020-02-25T05:26:59Z (GMT) by Jiuwang Yu Lu Wang Lidao Bao

In this study, a research strategy combining network pharmacological analysis, protein docking and molecular docking virtual computation was adopted. It was found that phillyrin and chlorogenic acid could block the combination of 2019-nCoV S-protein and ACE2 at the molecular level. Both can be used as potential inhibitors of 2019-nCoV for further research and development.