Direct Access to (±)-10-Desbromoarborescidine A from Tryptamine and Pentan-1,5-diol
2019-12-17T09:12:33Z (GMT) by
A single step synthetic strategy for (±)10- Desbromoarborescidine A is described. Starting from tryptamine and pentan-1,5-diol, this acceptorless dehydrogenative condensation process is efficiently catalyzed by a ruthenium complex featuring proton-responsive phosphine pyridone ligand.
Manuscript is available supporting material is available and includes experimental procedures, characterization of compounds, 1H, 13C NMR spectra and chromatograms.