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Abstract
Smart
polymeric systems are required that are able to release a therapeutic drug with
controlled delivery. Herein we investigated the pH triggered release of
ibuprofen from a polymeric nanoparticle system prepared using ring-opening
metathesis polymerisation. The co-polymerisation of ibuprofen and
poly(ethylene)glycol monomers followed by self-assembly produced a nanoparticle
system that was shown to be stable at neutral pH but releases ibuprofen in
alkaline conditions
Supplementary materials
Title
Controlled release of ibuprofen from polymeric nanoparticles - ESI
Description
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