Controlled Release of H2S and NO through Air-Stimulated Anion Exchange

2019-07-08T15:21:54Z (GMT) by Shinsuke Ishihara Nobuo Iyi
H2S and NO are gas molecules with physiological activities; solid materials that release these gases under safe and ubiquitous stimuli offer broad medical applications. Herein, we report solid materials that autonomously release ppm-level H2S or NO under air. HS or NO2 incorporated in the interlayer of layered double hydroxide (LDH), a clay mineral, is protonated by CO2 and H2O, yielding H2S or HNO2. HNO2 generates NO through disproportionation or reduction. Moreover, another NO-release method employs solid mixtures of NO2-incorporated LDH and FeSO4, wherein wet air triggers NO2 reduction with Fe2+ through anion exchange between NO2and SO42−. A potential application of the air-stimulated gas release system is demonstrated by creating a portable and battery-free NO inhaler for emergency treatment of respiratory distress.