Catalytic Hydrogenation of α,β-Unsaturated Carboxylic Acid Derivatives Using copper(I)/N-Heterocyclic Carbene Complexes

14 December 2018, Version 1
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

A simple and air-stable copper(I)/N-heterocyclic carbene complex enables the catalytic hydrogenation of hitherto unreactive enoates and enamides employing H2 as terminal reducing agent. This atom economic transformation replaces commonly employed hydrosilanes and can also be carried out in an asymmetric fashion.

Keywords

Hydrogen
Copper
NHC ligands
asymmetric catalysis
mechanisms

Supplementary materials

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Teichert conjugate hydrogenation ChemRXiv SI
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