A General Approach for Encapsulation of Biomolecules Using MOF Particles

Encapsulation of biomoleucles in metal organic frameworks (MOFs) has recently attracted significant interest because of the benign process including room temperature, neutral pH and without the requirement of any other chemical reagents. Also, these biomolecule incorporated MOFs (biomolecules@MOFs) have demonstrated their potential in biomolecule protection and controlled release for various applications such as drug delivery, vaccines, etc. This work aims to develop a general strategy to make biomolecules@MOFs via a biomimetic mineralization process.