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Stephenson_Kennedy_Manuscript_ChemRxiv_updated.docx (2.1 MB)

A Droplet Microfluidic Platform for High-Throughput Photochemical Reactions

preprint
submitted on 14.04.2020 and posted on 22.04.2020 by Alexandra Sun, Daniel Steyer, Anthony Allen, Emory Payne, Robert Kennedy, Corey Stephenson
We report the development of a droplet microfluidic/mass spectrometry platform for performing high-throughput photochemical reaction discovery on picomole scale. We also describe the successful translation of picomole scale flow screening conditions to millimole scale flow operations, highlighting the utility of this platform for discovery chemistry applications.

Funding

GOALI: Biocatalysis Development using High-throughput Droplet Microfluidics and Mass Spectrometry

Directorate for Engineering

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Redox catalysis strategies for synthesis

Directorate for Mathematical & Physical Sciences

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History

Email Address of Submitting Author

crjsteph@umich.edu

Institution

University of Michigan

Country

USA

ORCID For Submitting Author

0000-0002-2443-5514

Declaration of Conflict of Interest

none

Version Notes

Updated version fixed grant acknowledgement

Exports