A Convenient Two-Step Synthesis of Coenzyme Q1

<p>A convenient method for the preparation of Coenzyme Q<sub>1</sub> from the cheap and readily available 3,4,5-Trimethoxytoluene was developed. CoQ<sub>1 </sub>was synthesized in moderate yield by a two-step procedure involving the key reaction of allyl bromide with CoQ<sub>0 </sub>through a redox chain reaction. The reaction is efficient and could be used for the synthesis of other CoQ compounds.</p>